Aikawa-Aikawa Laboratories

Cardiovascular Division, Brigham and Women's Hospital

Kawakami, Ryo

Kawakami, Ryo

Research Fellow

Dr. Ryo Kawakami graduated from Kagawa University School of Medicine in Kagawa, Japan in 2007. He started his career as a physician at Kagawa University Hospital where he specialized in Cardiology after two years of general training. In 2009, he entered into the Department of CardioRenal and Cerebrovascular Medicine at Kagawa University. He worked on research projects of atherosclerosis that included lipid metabolism and the effects of cardiac exercise training on cardiovascular diseases, besides his activities as a clinical researcher. In 2016, he joined at the group of Prof. Ryuichi Morishita at the Department of Clinical Gene Therapy, Osaka University. There he investigated the lipid mechanism and its clinical translation to develop a therapeutic vaccine for dyslipidemia. He has experienced various cardiovascular diseases as an Assistant Professor in the Department of CardioRenal and Cerebrovascular Medicine at Kagawa University from 2014 where he was funded by Research Fund for subsidy of Kagawa University.
He started working as a research fellow in the Center for Excellence in Vascular Biology, Cardiovascular Medicine, at Brigham and Women’s Hospital on January 3, 2017.

Publications

Kawakami R, Katsuki S, Travers R, Romero DC, Becker-Greene D, Passos LSA, Higashi H, Blaser MC, Sukhova GK, Buttigieg J, Kopriva D, Schmidt AM, Anderson DG, Singh SA, Cardoso L, Weinbaum S, Libby P, Aikawa M, Croce K, Aikawa E
S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus.
Arterioscler Thromb Vasc Biol. 2020;40(8):1838-1853 - PMID: 32460581 - PMCID: PMC7377960 - DOI: 10.1161/ATVBAHA.118.314087
Kawakami R, Nozato Y, Nakagami H, Ikeda Y, Shimamura M, Yoshida S, Sun J, Kawano T, Takami Y, Noma T, Rakugi H, Minamino T, Morishita R
Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice.
PLoS One. 2018;13(2):e0191895 - PMID: 29438441 - PMCID: PMC5811007 - DOI: 10.1371/journal.pone.0191895
Kawakami R, Matsumoto I, Shiomi M, Kurozumi M, Miyake Y, Ishizawa M, Ishikawa K, Murakami K, Noma T, Takagi Y, Nishimoto N, Minamino T
Role of the Low-Density Lipoprotein-Cholesterol/High-Density Lipoprotein-Cholesterol Ratio in Predicting Serial Changes in the Lipid Component of Coronary Plaque.
Circ J. 2017;81(10):1439-1446 - PMID: 28458377 - DOI: 10.1253/circj.CJ-16-1209
Kawakami R, Nakagami H, Noma T, Ohmori K, Kohno M, Morishita R.
RANKL system in vascular and valve calcification with aging
Inflammation and Regeneration. 2016;36:10