Dr. Toshiaki Nakano graduated from Kumamoto University School of Medicine in Kumamoto Japan in 1998. He started his career as a physician at Kyushu University Hospital where he specialized in Nephrology after two years of general training. In 2002, he entered into the Department of Pathophysiological and Experimental Pathology at Kyushu University. There he worked in vascular biology, especially in atherosclerosis, angiogenesis and chronic kidney disease. He also learned fundamental techniques of biochemistry and pathology and finished his Phd in 2006.
He treated many patients with kidney diseases and cardiovascular diseases as an Assistant Professor in the Kidney Care Unit at the Kyushu University Hospital from 2010 until 2013. He received the Excellent Award of Japanese Society of Nephrology in 2011. He was funded by the International Research Fund for Subsidy of Kyushu University School of Medicine Alumni.
He moved to the U.S to work as a research fellow in the Center for Excellence in Vascular Biology, Cardiovascular Medicine, at Brigham and Women’s Hospital on January 2, 2014.
Uremic Toxin Indoxyl Sulfate Promotes Pro-Inflammatory Macrophage Activation via the Interplay of OATB2B1 and Dll4-Notch Signaling: Potential Mechanism for Accelerated Atherogenesis in Chronic Kidney Disease.
Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.
Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development: Implications for the Treatment of Vein Graft Failure.
Impact of combined losartan/hydrochlorothiazide on proteinuria in patients with chronic kidney disease and hypertension.
Phosphate overload directly induces systemic inflammation and malnutrition as well as vascular calcification in uremia.
Relationship Between Residual Renal Function and Serum Fibroblast Growth Factor 23 in Patients on Peritoneal Dialysis.
Cerebral oxidative stress induces spatial working memory dysfunction in uremic mice: neuroprotective effect of tempol.
Chronic kidney disease is associated with neovascularization and intraplaque hemorrhage in coronary atherosclerosis in elders: results from the Hisayama Study.
The clinical utility of serum tartrate-resistant acid phosphatase 5b in the assessment of bone resorption in patients on peritoneal dialysis.
Effectiveness of lanthanum carbonate treatment used in combination with other phosphate binders in peritoneal dialysis patients.
Intern Med. 2012;51(16):2097-104 - PMID: 22892485
Validation of the exit-site scoring system recommended by the 2005 guidelines of the International Society for Peritoneal Dialysis.
Autocrine loop between vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 positively regulates tumor-associated lymphangiogenesis in oral squamoid cancer cells.
Association of kidney function with coronary atherosclerosis and calcification in autopsy samples from Japanese elders: the Hisayama study.
VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B.
A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes.
Nonendothelial mesenchymal cell-derived MCP-1 is required for FGF-2-mediated therapeutic neovascularization: critical role of the inflammatory/arteriogenic pathway.
The regulation of vascular endothelial growth factors (VEGF-A, -C, and -D) expression in the retinal pigment epithelium.
The effects of flavoxate hydrochloride on voltage-dependent L-type Ca2+ currents in human urinary bladder.
Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas.
Cytoplasmic expression and extracellular deposition of an antiangiogenic factor, pigment epithelium-derived factor, in human atherosclerotic plaques.
Angiogenesis and lymphangiogenesis and expression of lymphangiogenic factors in the atherosclerotic intima of human coronary arteries.