Aikawa-Aikawa Laboratories

Singh SA, Aikawa E, Aikawa M

Current Trends and Future Perspectives of State-of-the-Art Proteomics Technologies Applied to Cardiovascular Disease Research.

Circ J. 2016;80(8):1674-83 - PMID: 27430298 - DOI: 10.1253/circj.CJ-16-0499

Nakano Y, Matoba T, Tokutome M, Funamoto D, Katsuki S, Ikeda G, Nagaoka K, Ishikita A, Nakano K, Koga J, Sunagawa K, Egashira K

Nanoparticle-Mediated Delivery of Irbesartan Induces Cardioprotection from Myocardial Ischemia-Reperfusion Injury by Antagonizing Monocyte-Mediated Inflammation.

Sci Rep. 2016;6:29601 - PMID: 27403534 - PMCID: PMC4939605 - DOI: 10.1038/srep29601

Nakano T, Fukuda D, Koga JI, Aikawa M

Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.

Arterioscler Thromb Vasc Biol. 2016;36(10):2038-47 - PMID: 27562914 - PMCID: PMC5033717 - DOI: 10.1161/ATVBAHA.116.306926

Kramann R, Goettsch C, Wongboonsin J, Iwata H, Schneider RK, Kuppe C, Kaesler N, Chang-Panesso M, Machado FG, Gratwohl S, Madhurima K, Hutcheson JD, Jain S, Aikawa E, Humphreys BD

Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease.

Cell Stem Cell. 2016;19(5):628-642 - PMID: 27618218 - PMCID: PMC5097006 - DOI: 10.1016/j.stem.2016.08.001

Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabási AL, Boothby M, Aikawa E, Singh SA, Aikawa M

PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.

Nat Commun. 2016;7:12849 - PMID: 27796300 - PMCID: PMC5095532 - DOI: 10.1038/ncomms12849

Bischoff J, Casanovas G, Wylie-Sears J, Kim DH, Bartko P, Guerrero J, Dal-Bianco J, Beaudoin J, Garcia M, Sullivan S, Seybolt M, Morris B, Keegan J, Irvin W, Aikawa E, Levine R

CD45 Expression in Mitral Valve Endothelial Cells After Myocardial Infarction.

Circ Res. 2016;119(11):1215-1225 - PMID: 27750208 - PMCID: PMC5215059 - DOI: 10.1161/CIRCRESAHA.116.309598

Lee LH, Andraski AB, Pieper B, Higashi H, Sacks FM, Aikawa M, Singh SA

Automation of PRM-dependent D3-Leu tracer enrichment in HDL to study the metabolism of apoA-I, LCAT and other apolipoproteins.

Proteomics. 2016;:ePub - PMID: 27862954 - PMCID: PMC5572145 - DOI: 10.1002/pmic.201600085

Yabusaki K, Hutcheson JD, Vyas P, Bertazzo S, Body SC, Aikawa M, Aikawa E

Quantification of Calcified Particles in Human Valve Tissue Reveals Asymmetry of Calcific Aortic Valve Disease Development.

Front Cardiovasc Med. 2016;3:44 - PMID: 27867942 - PMCID: PMC5095138 - DOI: 10.3389/fcvm.2016.00044

Takase S, Matoba T, Nakashiro S, Mukai Y, Inoue S, Oi K, Higo T, Katsuki S, Takemoto M, Suematsu N, Eshima K, Miyata K, Yamamoto M, Usui M, Sadamatsu K, Satoh S, Kadokami T, Hironaga K, Ichi I, Todaka K, Kishimoto J, Egashira K, Sunagawa K.

Ezetimibe in Combination With Statins Ameliorates Endothelial Dysfunction in Coronary Arteries After Stenting: The CuVIC Trial (Effect of Cholesterol Absorption Inhibitor Usage on Target Vessel Dysfunction After Coronary Stenting), a Multicenter Randomized Controlled Trial.

Arterioscler Thromb Vasc Biol. 2016;37(2):350-358 - PMID: 27932353 - DOI: 10.1161/ATVBAHA.116.308388

Singh SA, Aikawa M

Unbiased and targeted mass spectrometry for the HDL proteome.

Curr Opin Lipidol. 2016;28(1):68-77 - PMID: 28002079 - PMCID: PMC6211176 - DOI: 10.1097/MOL.0000000000000374

Hjortnaes J, Keegan J, Bruneval P, Schwartz E, Schoen FJ, Carpentier A, Levine RA, Hagège A, Aikawa E

Comparative Histopathological Analysis of Mitral Valves in Barlow Disease and Fibroelastic Deficiency.

Semin Thorac Cardiovasc Surg. 2016;28(4):757-767 - PMID: 28417861 - DOI: 10.1053/j.semtcvs.2016.08.015

Kawakami R, Nakagami H, Noma T, Ohmori K, Kohno M, Morishita R.

RANKL system in vascular and valve calcification with aging

Inflammation and Regeneration. 2016;36:10

Passos LS, Villani FN, Magalhães LM, Gollob KJ, Antonelli LR, Nunes MC, Dutra WO

Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease.

J Infect Dis. 2016;214(6):935-44 - PMID: 27368347 - DOI: 10.1093/infdis/jiw266

Fiuza JA, Gannavaram S, Santiago Hda C, Selvapandiyan A, Souza DM, Passos LS, de Mendonça LZ, Lemos-Giunchetti Dda S, Ricci ND, Bartholomeu DC, Giunchetti RC, Bueno LL, Correa-Oliveira R, Nakhasi HL, Fujiwara RT

Vaccination using live attenuated Leishmania donovani centrin deleted parasites induces protection in dogs against Leishmania infantum.

Vaccine. 2014;33(2):280-8 - PMID: 25475955 - DOI: 10.1016/j.vaccine.2014.11.039

Hojo-Souza NS, Pereira DB, Mendes TA, Passos LS, Gazzinelli-Guimarães AC, Gazzinelli-Guimarães PH, Tada MS, Zanini GM, Bartholomeu DC, Fujiwara RT, Bueno LL

CD4+ T cells apoptosis in Plasmodium vivax infection is mediated by activation of both intrinsic and extrinsic pathways.

Malar J. 2015;14:5 - PMID: 25559491 - PMCID: PMC4326293 - DOI: 10.1186/1475-2875-14-5

Hojo-Souza NS, Pereira DB, Passos LS, Gazzinelli-Guimarães PH, Cardoso MS, Tada MS, Zanini GM, Bartholomeu DC, Fujiwara RT, Bueno LL

Phenotypic profiling of CD8(+) T cells during Plasmodium vivax blood-stage infection.

BMC Infect Dis. 2015;15:35 - PMID: 25636730 - PMCID: PMC4329216 - DOI: 10.1186/s12879-015-0762-x

Gazzinelli-Guimarães PH, Gazzinelli-Guimarães AC, Silva FN, Mati VL, Dhom-Lemos Lde C, Barbosa FS, Passos LS, Gaze S, Carneiro CM, Bartholomeu DC, Bueno LL, Fujiwara RT

Parasitological and immunological aspects of early Ascaris spp. infection in mice.

Int J Parasitol. 2013;43(9):697-706 - PMID: 23665127 - DOI: 10.1016/j.ijpara.2013.02.009

Coelho-dos-Reis JG, Passos L, Duarte MC, Araújo MG, Campi-Azevedo AC, Teixeira-Carvalho A, Peruhype-Magalhães V, Trindade BC, Dos Santos Dias R, Martins ML, Carneiro-Proietti AB, Guedes AC, Gonçalves DU, Martins-Filho OA

Immunological profile of HTLV-1-infected patients associated with infectious or autoimmune dermatological disorders.

PLoS Negl Trop Dis. 2013;7(7):e2328 - PMID: 23936564 - PMCID: PMC3723575 - DOI: 10.1371/journal.pntd.0002328