Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy.
J Biomed Opt. 2006;11(2):021009 - PMID: 16674184 - DOI: 10.1117/1.2186337
Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells.
Circulation. 2006;113(19):2301-12 - PMID: 16682613 - DOI: 10.1161/CIRCULATIONAHA.105.605121
Cellular imaging of inflammation in atherosclerosis using magnetofluorescent nanomaterials.
Mol Imaging. 2006;5(2):85-92 - PMID: 16954022
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease.
Proc Natl Acad Sci U S A. 2006;103(27):10340-10345 - PMID: 16801531 - PMCID: PMC1502459 - DOI: 10.1073/pnas.0604260103
Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.
Circulation. 2006;114(14):1504-11 - PMID: 17000904 - DOI: 10.1161/CIRCULATIONAHA.106.646380
Human pulmonary valve progenitor cells exhibit endothelial/mesenchymal plasticity in response to vascular endothelial growth factor-A and transforming growth factor-beta2.
Circ Res. 2006;99(8):861-9 - PMID: 16973908 - PMCID: PMC2810464 - DOI: 10.1161/01.RES.0000245188.41002.2c
Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease.
Circulation. 2007;115(3):377-86 - PMID: 17224478 - DOI: 10.1161/CIRCULATIONAHA.106.654913
Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata.
Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo.
Circulation. 2007;115(11):1384-91 - PMID: 17339546 - DOI: 10.1161/CIRCULATIONAHA.106.663351
Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor.
Circulation. 2007;115(17):2292-8 - PMID: 17420353 - DOI: 10.1161/CIRCULATIONAHA.106.660340
Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct.
Circ Res. 2007;100(8):1218-25 - PMID: 17379832 - DOI: 10.1161/01.RES.0000265064.46075.31
Healing and remodeling of bioengineered pulmonary artery patches implanted in sheep.
Cardiovasc Pathol. 2007;16(5):277-82 - PMID: 17868878 - DOI: 10.1016/j.carpath.2007.03.008
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis.
Circulation. 2007;117(3):379-87 - PMID: 18158358 - PMCID: PMC2663426 - DOI: 10.1161/CIRCULATIONAHA.107.741181
Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis.
Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.
Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051 - DOI: 10.1161/CIRCULATIONAHA.107.756510
Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis.
Circulation. 2008;118(18):1802-9 - PMID: 18852366 - PMCID: PMC2729441 - DOI: 10.1161/CIRCULATIONAHA.108.785881
Simplified syntheses of complex multifunctional nanomaterials.
Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase.
Proc Natl Acad Sci U S A. 2008;105(47):18584-9 - PMID: 19011099 - PMCID: PMC2587593 - DOI: 10.1073/pnas.0803945105
Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo.
Proc Natl Acad Sci U S A. 2008;105(49):19126-31 - PMID: 19015534 - PMCID: PMC2614726 - DOI: 10.1073/pnas.0804798105
Notch signaling in cardiovascular disease and calcification.
Curr Cardiol Rev. 2008;4(3):148-56 - PMID: 19936191 - PMCID: PMC2780816 - DOI: 10.2174/157340308785160552
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Neuroimage. 2008;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022
Molecular imaging of innate immune cell function in transplant rejection.
Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889 - DOI: 10.1161/CIRCULATIONAHA.108.796888
Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.
Diffusion spectrum MRI tractography reveals the presence of a complex network of residual myofibers in infarcted myocardium.
Circ Cardiovasc Imaging. 2009;2(3):206-12 - PMID: 19808594 - PMCID: PMC2760045 - DOI: 10.1161/CIRCIMAGING.108.815050
The antiproliferative cytostatic effects of a self-activating viridin prodrug.
Mol Cancer Ther. 2009;8(6):1666-75 - PMID: 19509266 - PMCID: PMC2740925 - DOI: 10.1158/1535-7163.MCT-08-1012
Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation.
Circulation. 2009;120(4):334-42 - PMID: 19597052 - PMCID: PMC2752046 - DOI: 10.1161/CIRCULATIONAHA.108.846782
Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors.
Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251 - DOI: 10.1161/ATVBAHA.109.193086
Identification of splenic reservoir monocytes and their deployment to inflammatory sites.
Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure.
Circ Cardiovasc Imaging. 2009;2(6):468-75 - PMID: 19920045 - PMCID: PMC2782621 - DOI: 10.1161/CIRCIMAGING.109.863779
18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis.
JACC Cardiovasc Imaging. 2009;2(10):1213-22 - PMID: 19833312 - PMCID: PMC2773129 - DOI: 10.1016/j.jcmg.2009.04.016
Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia.
Circ Cardiovasc Imaging. 2009;2(6):460-7 - PMID: 19920044 - PMCID: PMC2780438 - DOI: 10.1161/CIRCIMAGING.109.859678
Oxazine conjugated nanoparticle detects in vivo hypochlorous acid and peroxynitrite generation.
Endothelial progenitor cells as a sole source for ex vivo seeding of tissue-engineered heart valves.
Tissue Eng Part A. 2010;16(1):257-67 - PMID: 19698056 - PMCID: PMC2811057 - DOI: 10.1089/ten.TEA.2009.0424
The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells.
Biomaterials. 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971 - DOI: 10.1016/j.biomaterials.2009.10.019
Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study.
Tissue Eng Part C Methods. 2010;16(4):597-607 - PMID: 19751103 - PMCID: PMC7875113 - DOI: 10.1089/ten.TEC.2009.0466
In vivo monitoring of function of autologous engineered pulmonary valve.
J Thorac Cardiovasc Surg. 2010;139(3):723-31 - PMID: 20176213 - DOI: 10.1016/j.jtcvs.2009.11.006
Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.
J Am Coll Cardiol. 2010;55(15):1629-38 - PMID: 20378083 - PMCID: PMC2852892 - DOI: 10.1016/j.jacc.2009.08.089
Expression of the familial cardiac valvular dystrophy gene, filamin-A, during heart morphogenesis.
Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation.
Eur Heart J. 2010;31(16):1975-84 - PMID: 20601388 - PMCID: PMC2921509 - DOI: 10.1093/eurheartj/ehq237
Pioglitazone suppresses inflammation in vivo in murine carotid atherosclerosis: novel detection by dual-target fluorescence molecular imaging.
Arterioscler Thromb Vasc Biol. 2010;30(10):1933-9 - PMID: 20689078 - PMCID: PMC3030475 - DOI: 10.1161/ATVBAHA.110.206342
Mitral valve endothelial cells with osteogenic differentiation potential.
Arterioscler Thromb Vasc Biol. 2010;31(3):598-607 - PMID: 21164078 - PMCID: PMC3210435 - DOI: 10.1161/ATVBAHA.110.216184
Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata.
Eur Heart J. 2011;32(21):2713-22 - PMID: 21292680 - PMCID: PMC3205479 - DOI: 10.1093/eurheartj/ehq519
Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques.
Sci Transl Med. 2011;3(84):84ra45 - PMID: 21613624 - PMCID: PMC3112179 - DOI: 10.1126/scitranslmed.3001577
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation.
Progenitor cells confer plasticity to cardiac valve endothelium.
J Cardiovasc Transl Res. 2011;4(6):710-9 - PMID: 21789724 - DOI: 10.1007/s12265-011-9312-0
Cardiovascular calcification: an inflammatory disease.
Circ J. 2011;75(6):1305-13 - PMID: 21566338 - DOI: 10.1253/circj.cj-11-0395
Molecular imaging insights into early inflammatory stages of arterial and aortic valve calcification.
Circ Res. 2011;108(11):1381-91 - PMID: 21617135 - PMCID: PMC3139950 - DOI: 10.1161/CIRCRESAHA.110.234146
Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.
Circulation. 2011;124(16):1783-91 - PMID: 22007101 - PMCID: PMC3306614 - DOI: 10.1161/CIRCULATIONAHA.110.006767
Vasculitis: molecular imaging by targeting the inflammatory enzyme myeloperoxidase.
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